ORG MED LEC: most successful derivative of thienamycin

primary group is converted to nonnucleophilic basic function

rapid degradation by renal peptidases

Question

most successful derivative of thienamycin

primary group is converted to nonnucleophilic basic function

rapid degradation by renal peptidases

LEIGHTON DWIGHT OBILLOS · Accepted Answer

Imipenem-Cilastatin (BN: Primaxin)

Cilastatin - inhibitor of DHP-I> longer DOA

Most successful derivative of thienamycin primary group is converted to nonnucleophilic basic function rapid degradation by renal peptidases