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MBS1002 Biomedical Approaches

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Question:

What is the difference between active immunization and passive transfer in the generation of animal models?

Author: Mirte Schattorie



Answer:

In active immunization, an animal model is induced through exposure to the antigen, after which the animal develops its own antibodies to this antigen. in passive transfer, an animal model is induced through the administration of serum, purified immunoglobulins, monoclonal antibodies or antibody-producing cells, which are isolated from a diseased organism. antibodies are present directly, and this model can be used to study the acute effects of a disease.


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