How can the efficacy of a MG animal model be assessed?

- clinical score: score of animal weakness prior and after induction, scores from 0 (no weakness) through 4 (death). - measures of weakness and fatigability, through grip meter or mesh test. - electromyography: measurement of muscle action potential, and thus muscle weakness/strength. - immunofluorescence or electron microscopy of the neuromuscular junction to assess absence of AChR. - radioimmunoassay to measure AChR concentration.