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From course:

MANUFACTURE FINALS

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Question:

MOTTLING CAUSES: (STATE THE CAUSES & THEIR REMEDIES)

Author: LEIGHTON DWIGHT OBILLOS



Answer:

1 DIFFERENT COLORS OF INGREDIENTS - REMEDY: CHOOSE EXCIPIENTS that has the SAME COLOR with ACTIVE INGREDIENTS 2 COLORED DEGRADATION PRODUCTS OF THE DRUG - REMEDY: USE DIES to MASK THE DEGRADATION product 3 COLOR-DYE MIGRATION DURING DRYING OF GRANULES - REMEDY: REDUCE THE DRYING TEMPERATURE or change the solvent system


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