What are pros and cons of NGS?

Pros: generates data from hundreds of sequences simultaneously, more sensitive to low frequency variations, little amount of DNA needed (because amplification is done), fast (human genome can be sequenced overnight), allows for multiplexing, cost effective, high reproducibility, a priori knowledgde of the genome is not required (adaptors do not bind complementary). cons: large infrastructure needed (sequencer, computer, storage, expertise), cheap per base but it generates so many bases that it is overall still expensive.