What is left ventricular remodeling?

Changes in LV mass, volume, shape, composition after cardiac injury May contribute in progression to HF, can be reversed by medical therapy/device to get better outcomes of HFrEF, so our goal is to prevent remodeling which will cause overactivation of neurohormones, apoptosis, hemodynamic alterations leading to heart failure Predictors of reverse remodeling is seen by LVEF and HF onset (reverse if non-ischemic, shorter time of HF, lower LVEF, and biomarkers low)