Question:
How is dx of AIH done?
Author: H KAnswer:
Scorring system Gender (female +2), ALT (>3 -2, <1.5 +2), Serum glob (1-1.5 +1, 1.5-2 +2, >2 +3), Viral sero (+ -3, - +3), drug (+ -4, + +1), Alcohol intake (>60g/dl -2, <25 +2), AMA (+ -4), DR3/4 (+ +1), Histology (+3 if interface hep, +1 if lymphoplasmacytic infiltrate (+1 each), -3 if biliary change (-3 each), -5 if absence of all of the above) ANA/SMA/LKM1 (1:40 +1, 1:80 +2, >1:80 +3) other autoAb/autoimmune disease (+2 each), responsive to therapy (if complete +2 if relapse +3) Total score of 10 or higher is positive result
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