Question:
What are disorders of platelets?
Author: H KAnswer:
Deficiency (thrombocytopenia) leads to bruising and bleeding, caused by autoimmune/ drugs Increased (thrombocytosis) cause clots and bleeding Sometimes function impaired (use of aspirin) Deficiency in proteins of clotting can be inherited disorder or later in life (Hemophilia A deficiency in factor VIII most imp) Acquired can be severe infection/ complication after birth. Clot problems are more important than bleeding disorders (increased susceptibility for clotting) and risk increases w/bed rest/ surgery/ arrhythmia, so use of anti-thrombotics is very widely seen
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