TOXICOLOGY: 1 → A process that involves a selective clonal
expansion of initiated cells to produce or become
preneoplastic focal lesion
→ The exogenous and endogenous particles that
usually operate at this stage is called the tumor
promoter

2 → can change the gene expression which can
lead to proliferation (continuous) or inhibition of
apoptosis process
→ Dose and frequency dependent
→ Renders organ specific effect

Question

1 → A process that involves a selective clonal
expansion of initiated cells to produce or become
preneoplastic focal lesion
→ The exogenous and endogenous particles that
usually operate at this stage is called the tumor
promoter

2 → can change the gene expression which can
lead to proliferation (continuous) or inhibition of
apoptosis process
→ Dose and frequency dependent
→ Renders organ specific effect

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 Promotion phase

2 Tumor promoter

→ Reversible process in term of removal of
promoting agents or tumor promoter → that
results to focal cells or focal lesions returning to a
single initiated cells

TOXICOLOGY

1 Promotion phase 2 Tumor promoter → Reversible process in term of removal of promoting agents or tumor promoter → that results to focal cells or focal lesions returning to a single initiated cells

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