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Anapath

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Question:

How is morphology of burkitt lymphoma?

Author: H K



Answer:

• mature aggressive Bcell neoplasm • monomorphic, medium-sized cells • multiple small nucleoli, • a germinal center B-cell phenotype, • starry sky pattern • high mitotic index • numerous apoptotic cells • CD20 and CD10 positivity. • Absence or (rarely) weak expression of BCL2. • Usually strong expression of MYC (in >80% of cells) • a high proliferation index (Ki67 index >95%)


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Author

H K
H K