Question:
What are neoplasms in situ?
Author: H KAnswer:
➢ Most testicular tumors in postpubertal males arise from germ cell neoplasia in situ. ➢ This precursor lesion is present in conditions associated with a high risk for developing germ cell tumors (e.g., cryptorchidism, dysgenetic gonads) ➢ Exhibits the same abnormality of chromosome 12 that is characteristic of fully developed germ cell tumors. ➢ Often found in “normal” testis adjacent to full-blown germ cell tumors.
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H K![H K](https://lh4.googleusercontent.com/-V3rEIOcuFis/AAAAAAAAAAI/AAAAAAAAAAA/AMZuucnhTzvoiq2vqvBJhe7t9kqRkO_jNw/s96-c/photo.jpg)