How is teratoma with malignant transformations?

➢ Rarely, non–germ cell tumors may arise in teratoma—a phenomenon referred to as teratoma with malignant transformation ➢ Such neoplasms include squamous cell carcinoma, adenocarcinoma, and various sarcomas ➢ These non–germ cell malignancies do not respond to therapies that are effective against metastatic germ cell tumors thus, the only hope for cure in such cases resides in surgical resection