Irritable Bowel Syndrome (IBS)
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| 🇬🇧 | 🇬🇧 |
| Define Irritable Bowe Syndrome (IBS) | A recurrent abdominal pain associated with defecation, changes in frequency or consistency of stool. |
| Causes of IBS | - unknown - may precipitate by stress, emotion or some drugs |
| Pathophysiology of IBS based on physiological factors (Give one only) | Altered intestinal motility - postprandial pain - ingestion of food high in FODMAPs (Fermentable Oligosaccharide Disaccharide Monosaccharide and Polyols) are poorly absorbed in small intestine results in increase colonic motility and secretion Increase intestinal sensitivity - hypersensitivity to normal amount of intraluminal secretion - increased pain perception to the presence normal intestinal gas - rectal sensitivity during menses Genetic/ environmental factors - began after acute gastroenteritis |
| Pathophysiology of IBS based on psychological factors | Stress, anxiety, depression |
| Sign and symptoms of IBS | 1. Adolescence/ 20s 2. Triggered by food or stress or drugs 3. Abdominal discomfort 4. Pain related to defecation, changes in frequency or consistency of stool 5. Feeling of incomplete evacuation/ dyspepsia/ abdominal bloating 6. Headache/ fibromyalgia |
| Differential diagnosis of IBS | - lactose intolerance - giardiasis - celiac disease - drug induced diarrhea - early IBD |
| Treatment of IBS | - low FODMAPs diet - anti diarrheal - anti muscarinic - laxatives - manage stress |