Pharmacology [LE 2]
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131 questions
| 🇬🇧 | 🇬🇧 |
| Long-acting A1 agonists used as non-oral nasal decongestants | Oxymetazoline, Xylometazoline |
| Short-acting A1 agonists used as non-oral nasal decongestants | Tetrahydrozoline, Naphazoline |
| The protoype drug for A1 agonists | Phenylephrine |
| Effect of Phenylephrine on the eyes | Mydriasis |
| Adverse effect of Phenylpropanolamine | Hemorrhagic stroke |
| Drug used in the manufacturing of methamphetamine | Pseudoephedrine |
| A1 agonists used for stress incontinence | Pseudoephedrine, Ephedrine |
| Therapeutic use of midodrine | Chronic hypotension |
| Therapeutic use of A2 agonists | Hypertension |
| Examples of A2 agonists | Clonidine, Methyldopa, Guanfacine |
| Effect of Isoproterenol on CO, SP | Increased |
| Protoype B1-Selective agonist drug | Dobutamine |
| Therapeutic use of Dobutamine | Chronic Heart Failure, Acute Myocardial Infarction |
| Prototype B2-selective agonist drugs | Terbutaline, Salbutamol |
| Agents of choice for nocturnal asthma | Salmeterol, Formoterol |
| Adverse effect of Salbutamol | Tremors and tachycrdia |
| Which drugs have a black box warning? | Arformoterol, Salmeterol, Formoterol |
| Which drug is used as monotherapy for COPD? | Indacaterol |
| Therapeutic uses of Carmoterol | Asthma, COPD |
| Besides Indacaterol, which other ulta long-lasting drugs are used for COPD treatment? | Bambuterol, Olodaterol, Vilanterol |
| B3-selective drug | Mirabegron |
| Therapeutic use of Mirabegron | Over-active Bladder |
| Adverse effect of Mirabegron | Hypertension |
| Effect on Dopamine on blood vessels in LOW doses | Vasodilation |
| Synthetic analog of Dopamine | Dopexamine |
| D1-Selective drug | Fenoldopam |
| Effect of Fenoldopam on blood vessels | Vasodilation |
| Which drug is commonly known as shabu? | Methamphetamine |
| Which indirect-acting, amphetamine-like drugs are sed as an appetite stimulant? | Phenmetrazine, Methamphetamine |
| Therapeutic use of Modafinil | Narcolepsy |
| Which "drug" is rapidly metabolized by MAO and is therefore should not be taken with MAO inhibitors? | Tyramine |
| Which drugs inhibit NET? | Atomoxetine, Reboxetine |
| Therapeutic use of Reboxetine | Depression, Narcolepsy |
| Which drugs are used to treat pain from fibromyalgia? | Duloxetine, Milnacipran |
| Which drug is an example of a TCA? | Imipramine |
| A2 agonist drugs given to patients with glaucoma | Apraclonidine, Brimonidine |
| Which A2 agonist does NOT cross the BBB? | Apraclonidine |
| Drugs of the Imidazoline group besides Clonidine given for hypertension | Rilmenidine, Moxonidine |
| Effect of A1 blockade on blood vessels | Vasodilation |
| Drug examples of reversible Alpha blockers | Prazosin, Tamsulosin, Phentolamine |
| Drug prototype for reversible Alpha blocker | Phentolamine |
| Reversible, non-selective Alpha blocker | Phentolamine |
| Major adverse effect of Phentolamine on CVS | Hypotension |
| Alpha blocker given to reverse local anaesthesia | Phentolamine |
| Alpha blocker given during hypertensive crisis | Phentolamine |
| Alpha blocker given for peripheral vascular diseases like Raynaud's Phenomenon and Burger's Disease | Phenoxybenzamine |
| Prototype of irreversible Alpha blockers | Phenoxybenzamine |
| Non-selective A1ABD blockers | Prazosin, Terazosin, Doxazosin |
| Selective A1A blockers | Tamsulosin, Alfuzosin, Silodosin |
| Which A1 blockers are less likely to cause first dose effect and lipid profile changes? | Tamsulosin, Silodosin |
| Which selective A1 blockers may cause abnormal ejaculation and Intraoperative Floppy Iris Syndrome? | Tamsulosin, Silodosin |
| Which A1 blockers are given to patients with hypertension AND patients with BPH? | Prazosin, Terazosin, Doxazosin |
| Which A1 blockers are given to patients with BPH only? | Alfuzosin, Tamsulosin, Silodosin |
| Selective competitive A2 blocker | Yohimbine |
| Non-selective, first generation beta blockers | Propranolol, Nadolol, Timolol |
| Non-selective, third generation beta blockers | Labetalol, Carvedilol, Carteolol |
| Selective, second generation B1 blockers | Metoprolol, Atenolol, Esmolol |
| Selective, third generation B1 blockers | Nebivolol, Betaxolol, Celiprolol |
| Beta blockers with intrinsic sympathetic activity | Pindolol, Acebutolol, Bucindolol |
| Beta blockers with membrane stabilizing activity | Propranolol, Carvedilol, Acebutolol |
| Drugs that produce both alpha and beta blockade | Carvedilol, Labetalol, Bucindolol |
| Which beta blockers induce peripheral vasodilation?Nenbivolol, Ceriprolol | Nebivolol, Celiprolol, Labetalol |
| Which beta blockers induce NO production? | Nebivolol, Celiprolol, Labetalol |
| Which beta blockers are highly lipophilic? | Propranolol, Penbutolol |
| Which beta blockers are highly hydrophilic? | Nadolol, Atenolol, Esmolol |